Comparative study of oral terbinafine vs. oral griseofulvin in the management of tinea capitis

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Comparative evaluation of griseofulvin, terbinafine and fluconazole in the treatment of tinea capitis.

Tinea capitis (TC) is a common childhood fungal infection which, if untreated, can cause long-term scarring. A number of antifungal drugs with proven efficacy are available for the treatment of TC. However, varying dosage schedules, changes in epidemiology, and rising drug resistance are factors that hamper treatment in some cases. A prospective, non-blinded, cross-sectional study of three comm...

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Oral terbinafine in the treatment of griseofulvin-resistant Tinea capitis et faciei et corporis in a 10-month-old girl.

Sir, Tinea capitis occurs worldwide. It is primarily a disease of childhood but in most cases oral therapy is necessary (1). Currently, triazoles and allylamines are increasingly applied in addition to the well-known antimycotics ketoconazole and griseofulvin (2 ^ 4). Terbina¢n is the ¢rst oral active allylamine, and although it has been available for several years experience in children is lim...

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Meta-analysis: griseofulvin efficacy in the treatment of tinea capitis.

Despite its long history in clinical use, reported efficacy rates of griseofulvin remain highly variable. A meta-analysis of clinical trials of griseofulvin use in tinea capitis was performed to determine mean griseofulvin efficacy. A review of the literature identified 7 studies. When all 7 studies were pooled, the overall mean effective cure (negative KOH and culture) of griseofulvin at 4 to ...

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Comparison of the efficacy of Fluconazole and Griseofulvin in Tinea Capitis

Background: Tinea capitis is a relatively common fungal infection in children. Although several oral anti-fungal agents have been used in the treatment of tinea capitis, griseofulvin has been considered as the treatment of choice for a long time. Objective: To compare the therapeutic effects of fluconazole with griseofulvin on tinea capitis. Patients and Methods: Through a randomized, single-bl...

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ژورنال

عنوان ژورنال: International Journal of Research in Dermatology

سال: 2019

ISSN: 2455-4529

DOI: 10.18203/issn.2455-4529.intjresdermatol20193242